Drug-Induced QT Prolongation And Torsades de Pointes.
نویسندگان
چکیده
Torsades de pointes (TdP)-an uncommon but life-threatening polymorphic ventricular tachycardia-is almost always drug induced. The authors describe the causes, risk factors, symptoms, diagnosis, and treatment of TdP.
منابع مشابه
QT Interval Prolongation as a Biomarker for Torsades de Pointes and Sudden Death in Drug Development
Prolongation of the QT interval on the surface 12-lead electrocardiogram is widely accepted as a biomarker for the potential of a drug to produce torsades de pointes and/or sudden death. Detection of drug-induced prolongation of the QT interval in animals and man is frequently confounded by extrinsic and intrinsic factors that limit the ability to detect a true drug effect. In particular drugs ...
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ورودعنوان ژورنال:
- Drug safety
دوره 41 1 شماره
صفحات -
تاریخ انتشار 2003